How do eubacterial organisms manage aggregation-prone proteome? [v1; ref status: indexed, http://f1000r.es/3k3]
Eubacterial genomes vary considerably in their nucleotide composition.The percentage of genetic material constituted by guanosine and cytosine (GC) nucleotides ranges from 20% to 70%.It has been posited that GC-poor organisms are more dependent on protein folding machinery.Previous studies have ascribed this to the accumulation of mildly deleteriou